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Computational identification of signals predictive for nuclear RNA exosome degradation pathway targeting

The RNA exosome degrades transcripts in the nucleoplasm of mammalian cells. Its substrate specificity is mediated by two adaptors: the ‘nuclear exosome targeting (NEXT)’ complex and the ‘poly(A) exosome targeting (PAXT)’ connection. Previous studies have revealed some DNA/RNA elements that differ be...

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Detalles Bibliográficos
Autores principales:	Wu, Mengjun, Schmid, Manfred, Jensen, Torben Heick, Sandelin, Albin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Standard Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477074/ https://www.ncbi.nlm.nih.gov/pubmed/36128426 http://dx.doi.org/10.1093/nargab/lqac071

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