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Artemisinin analog SM934 alleviates epithelial barrier dysfunction via inhibiting apoptosis and caspase-1-mediated pyroptosis in experimental colitis

Intestinal barrier disruption due to the intestinal epithelial cells’ (IECs) death is one of the critical pathological features of inflammatory bowel diseases (IBDs). SM934, an artemisinin analog, has previously been proven to ameliorate colitis induced by dextran sulfate sodium (DSS) in mice by sup...

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Detalles Bibliográficos
Autores principales:	Shao, Meijuan, Yan, Yuxi, Zhu, Fenghua, Yang, Xiaoqian, Qi, Qing, Yang, Fangming, Hao, Tingting, Lin, Zemin, He, Peilan, Zhou, Yu, Tang, Wei, He, Shijun, Zuo, Jianping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477143/ https://www.ncbi.nlm.nih.gov/pubmed/36120344 http://dx.doi.org/10.3389/fphar.2022.849014

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