An innovative strategy to identify new targets for delivering antibodies to the brain has led to the exploration of the integrin family

BACKGROUND: Increasing brain exposure of biotherapeutics is key to success in central nervous system disease drug discovery. Accessing the brain parenchyma is especially difficult for large polar molecules such as biotherapeutics and antibodies because of the blood-brain barrier. We investigated a n...

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Detalles Bibliográficos
Autores principales: Cegarra, Céline, Cameron, Béatrice, Chaves, Catarina, Dabdoubi, Tarik, Do, Tuan-Minh, Genêt, Bruno, Roudières, Valérie, Shi, Yi, Tchepikoff, Patricia, Lesuisse, Dominique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477330/
https://www.ncbi.nlm.nih.gov/pubmed/36108060
http://dx.doi.org/10.1371/journal.pone.0274667

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477330/
https://www.ncbi.nlm.nih.gov/pubmed/36108060
http://dx.doi.org/10.1371/journal.pone.0274667

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