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In vitro sepsis induces Nociceptin/Orphanin FQ receptor (NOP) expression in primary human vascular endothelial but not smooth muscle cells

Sepsis is a dysregulated host response to infection that can cause widespread effects on other organs including cardiovascular depression, hypotension and organ failure. The receptor for Nociceptin/Orphanin FQ (N/OFQ), NOP is expressed on immune cells and these cells can release the peptide. Exogeno...

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Detalles Bibliográficos
Autores principales:	Bird, Mark F., Gallacher-Horley, Barbara, McDonald, John, McVey, David G., Al-Janabi, Fatin, Guerrini, Remo, Calo, Girolamo, Ye, Shu, Thompson, Jonathan P., Lambert, David G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477356/ https://www.ncbi.nlm.nih.gov/pubmed/36107872 http://dx.doi.org/10.1371/journal.pone.0274080

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