Combinatorial clustering of distinct DNA motifs directs synergistic binding of Caenorhabditis elegans dosage compensation complex to X chromosomes

Organisms that count X-chromosome number to determine sex utilize dosage compensation mechanisms to balance X-gene expression between sexes. Typically, a regulatory complex is recruited to X chromosomes of one sex to modulate gene expression. A major challenge is to determine the mechanisms that tar...

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Detalles Bibliográficos
Autores principales: Fuda, Nicholas J., Brejc, Katjuša, Kruesi, William S., Ralston, Edward J., Bigley, Rachel, Shin, Aram, Okada, Miki, Meyer, Barbara J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477397/
https://www.ncbi.nlm.nih.gov/pubmed/36067293
http://dx.doi.org/10.1073/pnas.2211642119

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