Multitarget drugs as potential therapeutic agents for alzheimer’s disease. A new family of 5-substituted indazole derivatives as cholinergic and BACE1 inhibitors

Multitarget drugs are a promising therapeutic approach against Alzheimer’s disease. In this work, a new family of 5-substituted indazole derivatives with a multitarget profile including cholinesterase and BACE1 inhibition is described. Thus, the synthesis and evaluation of a new class of 5-substitut...

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Detalles Bibliográficos
Autores principales: González-Naranjo, Pedro, Pérez, Concepción, González-Sánchez, Marina, Gironda-Martínez, Adrián, Ulzurrun, Eugenia, Bartolomé, Fernando, Rubio-Fernández, Marcos, Martin-Requero, Angeles, Campillo, Nuria E., Páez, Juan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477487/
https://www.ncbi.nlm.nih.gov/pubmed/36050834
http://dx.doi.org/10.1080/14756366.2022.2117315

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