Cargando…
Comprehensive analysis of the human ESCRT-III-MIT domain interactome reveals new cofactors for cytokinetic abscission
The 12 related human ESCRT-III proteins form filaments that constrict membranes and mediate fission, including during cytokinetic abscission. The C-terminal tails of polymerized ESCRT-III subunits also bind proteins that contain Microtubule-Interacting and Trafficking (MIT) domains. MIT domains can...
Autores principales: | Wenzel, Dawn M, Mackay, Douglas R, Skalicky, Jack J, Paine, Elliott L, Miller, Matthew S, Ullman, Katharine S, Sundquist, Wesley I |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477494/ https://www.ncbi.nlm.nih.gov/pubmed/36107470 http://dx.doi.org/10.7554/eLife.77779 |
Ejemplares similares
-
ULK3 regulates cytokinetic abscission by phosphorylating ESCRT-III proteins
por: Caballe, Anna, et al.
Publicado: (2015) -
The Calpain-7 protease functions together with the ESCRT-III protein IST1 within the midbody to regulate the timing and completion of abscission
por: Paine, Elliott L, et al.
Publicado: (2023) -
ALIX and ESCRT-I/II function as parallel ESCRT-III recruiters in cytokinetic abscission
por: Christ, Liliane, et al.
Publicado: (2016) -
Identification of abscission checkpoint bodies as structures that regulate ESCRT factors to control abscission timing
por: Strohacker, Lauren K, et al.
Publicado: (2021) -
A cancer-associated polymorphism in ESCRT-III disrupts the abscission checkpoint and promotes genome instability
por: Sadler, Jessica B. A., et al.
Publicado: (2018)