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Collagen pre-strain discontinuity at the bone—Cartilage interface
The bone-cartilage unit (BCU) is a universal feature in diarthrodial joints, which is mechanically-graded and subjected to shear and compressive strains. Changes in the BCU have been linked to osteoarthritis (OA) progression. Here we report existence of a physiological internal strain gradient (pre-...
Autores principales: | Badar, Waqas, Ali, Husna, Brooker, Olivia N., Newham, Elis, Snow, Tim, Terrill, Nicholas J., Tozzi, Gianluca, Fratzl, Peter, Knight, Martin M., Gupta, Himadri S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477506/ https://www.ncbi.nlm.nih.gov/pubmed/36108273 http://dx.doi.org/10.1371/journal.pone.0273832 |
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