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Prediction of HIV sensitivity to monoclonal antibodies using aminoacid sequences and deep learning

MOTIVATION: Knowing the sensitivity of a viral strain versus a monoclonal antibody is of interest for HIV vaccine development and therapy. The HIV strains vary in their resistance to antibodies, and the accurate prediction of virus-antibody sensitivity can be used to find potent antibody combination...

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Detalles Bibliográficos
Autores principales: Dănăilă, Vlad-Rareş, Buiu, Cătălin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477525/
https://www.ncbi.nlm.nih.gov/pubmed/35876860
http://dx.doi.org/10.1093/bioinformatics/btac530

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