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Prediction of HIV sensitivity to monoclonal antibodies using aminoacid sequences and deep learning
MOTIVATION: Knowing the sensitivity of a viral strain versus a monoclonal antibody is of interest for HIV vaccine development and therapy. The HIV strains vary in their resistance to antibodies, and the accurate prediction of virus-antibody sensitivity can be used to find potent antibody combination...
Autores principales: | Dănăilă, Vlad-Rareş, Buiu, Cătălin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477525/ https://www.ncbi.nlm.nih.gov/pubmed/35876860 http://dx.doi.org/10.1093/bioinformatics/btac530 |
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