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lncRNA HOTTIP Recruits EZH2 to Inhibit PTEN Expression and Participates in IM Resistance in Chronic Myeloid Leukemia

OBJECTIVE: To investigate that HOTTIP suppressed PTEN gene expression and was involved in IM resistance in chronic myeloid leukemia through recruitment of EZH2 protein. METHODS: Seventy-one cases of bone marrow monocytes diagnosed with CML in the Second Hospital of Hebei Medical University from 2018...

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Detalles Bibliográficos
Autores principales:	Liu, Jing, Yang, Lin, Liu, Xiaojun, Liu, Lu, Liu, Menghan, Feng, Xuefeng, Luo, Jianmin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477575/ https://www.ncbi.nlm.nih.gov/pubmed/36117724 http://dx.doi.org/10.1155/2022/9993393

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