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Febuxostat Alleviates Allergic Rhinitis by Inhibiting Inflammation and Monocyte Adhesion in Human Nasal Epithelial Cells via Regulating KLF6

INTRODUCTION: Febuxostat is a novel inhibitor of xanthine oxidase that suppresses cell adhesion molecules-mediated (CAMs) inflammation by activating KLF6. In this study, we explored the therapeutic function and potential mechanisms of febuxostat against allergic rhinitis (AR). METHODS: We investigat...

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Detalles Bibliográficos
Autores principales:	Yao, Yuting, Wei, Ran, Jiang, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477640/ https://www.ncbi.nlm.nih.gov/pubmed/36118091 http://dx.doi.org/10.1155/2022/9092311

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