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Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation
Bacterial cell wall components provide various unique molecular structures that are detected by pattern recognition receptors (PRRs) of the innate immune system as non-self. Most bacterial species form a cell wall that consists of peptidoglycan (PGN), a polymeric structure comprising alternating ami...
Autores principales: | Stafford, Che A., Gassauer, Alicia-Marie, de Oliveira Mann, Carina C., Tanzer, Maria C., Fessler, Evelyn, Wefers, Benedikt, Nagl, Dennis, Kuut, Gunnar, Sulek, Karolina, Vasilopoulou, Catherine, Schwojer, Sophia J., Wiest, Andreas, Pfautsch, Marie K., Wurst, Wolfgang, Yabal, Monica, Fröhlich, Thomas, Mann, Matthias, Gisch, Nicolas, Jae, Lucas T., Hornung, Veit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477735/ https://www.ncbi.nlm.nih.gov/pubmed/36002575 http://dx.doi.org/10.1038/s41586-022-05125-x |
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