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Dendritic cell-derived IL-27 p28 regulates T cell program in pathogenicity and alleviates acute graft-versus-host disease

Interleukin 27 (IL-27), a heterodimeric cytokine composed of Epstein-Barr virus-induced 3 and p28, is a pleiotropic cytokine with both pro-and anti-inflammatory properties. However, the precise role of IL-27 in acute graft-versus-host disease is not yet fully understood. In this study, utilizing mic...

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Detalles Bibliográficos
Autores principales: Gong, Huanle, Ma, Shoubao, Chen, Jia, Yang, Bingyu, Liu, Shuangzhu, Liu, Xin, Han, Jingjing, Wu, Xiaojin, Lei, Lei, Yin, Zhinan, Sun, Hongjian, Yu, Di, Liu, Haiyan, Xu, Yang, Wu, Depei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477797/
https://www.ncbi.nlm.nih.gov/pubmed/36109504
http://dx.doi.org/10.1038/s41392-022-01147-z