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Magnetic resonance imaging analysis predicts nanoparticle concentration delivered to the brain parenchyma
Ultrasound in combination with the introduction of microbubbles into the vasculature effectively opens the blood brain barrier (BBB) to allow the passage of therapeutic agents. Increased permeability of the BBB is typically demonstrated with small-molecule agents (e.g., 1-nm gadolinium salts). Perme...
Autores principales: | Plaksin, Michael, Bercovici, Tiran, Sat Toltsis, Gabriella Gabi, Grinfeld, Javier, Shapira, Boaz, Zur, Yuval, de Picciotto, Rafi, Zadicario, Eyal, Siddeeq, Mustaffa, Wohl, Anton, Zibly, Zion, Levy, Yoav, Cohen, Zvi R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477799/ https://www.ncbi.nlm.nih.gov/pubmed/36109574 http://dx.doi.org/10.1038/s42003-022-03881-0 |
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