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In silico study on the Hepatitis E virus RNA Helicase and its inhibition by silvestrol, rocaglamide and other flavagline compounds

Hepatitis E Virus (HEV) follows waterborne or zoonotic/foodborne transmission. Genotype 3 HEV infections are worldwide spread, especially in swine populations, representing an emerging threat for human health, both for farm workers and pork meat consumers. Unfortunately, HEV in vitro culture and ana...

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Detalles Bibliográficos
Autores principales: Pedroni, Lorenzo, Dellafiora, Luca, Varrà, Maria Olga, Galaverna, Gianni, Ghidini, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477874/
https://www.ncbi.nlm.nih.gov/pubmed/36109625
http://dx.doi.org/10.1038/s41598-022-19818-w