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Induction of functional xeno-free MSCs from human iPSCs via a neural crest cell lineage

Mesenchymal stem/stromal cells (MSCs) are adult multipotent stem cells. Here, we induced MSCs from human induced pluripotent stem cells (iPSCs) via a neural crest cell (NCC) lineage under xeno-free conditions and evaluated their in vivo functions. We modified a previous MSC induction method to work...

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Detalles Bibliográficos
Autores principales: Kamiya, Daisuke, Takenaka-Ninagawa, Nana, Motoike, Souta, Kajiya, Mikihito, Akaboshi, Teppei, Zhao, Chengzhu, Shibata, Mitsuaki, Senda, Sho, Toyooka, Yayoi, Sakurai, Hidetoshi, Kurihara, Hidemi, Ikeya, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477888/
https://www.ncbi.nlm.nih.gov/pubmed/36109564
http://dx.doi.org/10.1038/s41536-022-00241-8