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Evaluating the efficacy and mechanism of metformin targets on reducing Alzheimer’s disease risk in the general population: a Mendelian randomisation study

AIMS/HYPOTHESIS: Metformin use has been associated with reduced incidence of dementia in diabetic individuals in observational studies. However, the causality between the two in the general population is unclear. This study uses Mendelian randomisation (MR) to investigate the causal effect of metfor...

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Detalles Bibliográficos
Autores principales:	Zheng, Jie, Xu, Min, Walker, Venexia, Yuan, Jinqiu, Korologou-Linden, Roxanna, Robinson, Jamie, Huang, Peiyuan, Burgess, Stephen, Au Yeung, Shiu Lun, Luo, Shan, Holmes, Michael V., Davey Smith, George, Ning, Guang, Wang, Weiqing, Gaunt, Tom R., Bi, Yufang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477943/ https://www.ncbi.nlm.nih.gov/pubmed/35902387 http://dx.doi.org/10.1007/s00125-022-05743-0

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