GDF15 : A modulator of immunity and a predictive biomarker of cardiovascular events : A strategy in COVID-19

In the recently published manuscript entitled “GDF15 a rising modulator of immunity and a strategy in Coronavirus disease 2019 (COVID-19) in relationship with iron metabolism” and we examined the potential properties of Growth and differentiation factor 15 (GDF15) as an emerging modulator of immunit...

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Detalles Bibliográficos
Autores principales: Rochette, Luc, Dogon, Geoffrey, Rigal, Eve, Zeller, Marianne, Vergely, Catherine, Cottin, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2023
Materias:
Mise Au Point
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477966/
https://www.ncbi.nlm.nih.gov/pubmed/36163282
http://dx.doi.org/10.1016/j.ancard.2022.09.001
Descripción
Sumario:In the recently published manuscript entitled “GDF15 a rising modulator of immunity and a strategy in Coronavirus disease 2019 (COVID-19) in relationship with iron metabolism” and we examined the potential properties of Growth and differentiation factor 15 (GDF15) as an emerging modulator of immunity in COVID-19. We commented new aspects of the biology of GDF15 and investigated the potential value of GDF15 as a biomarker. Is GDF15 a biomarker of the inflammatory process and oxidative stress state? Recently, it was reported that 1500 clinical trials related to COVID-19 have been registered, but none have yet found an optimal strategy. In these conditions, more clinical studies are needed before any of these agents can be considered antiviral agents.

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