GDF15 : A modulator of immunity and a predictive biomarker of cardiovascular events : A strategy in COVID-19

In the recently published manuscript entitled “GDF15 a rising modulator of immunity and a strategy in Coronavirus disease 2019 (COVID-19) in relationship with iron metabolism” and we examined the potential properties of Growth and differentiation factor 15 (GDF15) as an emerging modulator of immunit...

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Autores principales: Rochette, Luc, Dogon, Geoffrey, Rigal, Eve, Zeller, Marianne, Vergely, Catherine, Cottin, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Masson SAS. 2023
Materias:
Mise Au Point
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477966/
https://www.ncbi.nlm.nih.gov/pubmed/36163282
http://dx.doi.org/10.1016/j.ancard.2022.09.001
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author Rochette, Luc
Dogon, Geoffrey
Rigal, Eve
Zeller, Marianne
Vergely, Catherine
Cottin, Yves
author_facet Rochette, Luc
Dogon, Geoffrey
Rigal, Eve
Zeller, Marianne
Vergely, Catherine
Cottin, Yves
author_sort Rochette, Luc
collection PubMed
description In the recently published manuscript entitled “GDF15 a rising modulator of immunity and a strategy in Coronavirus disease 2019 (COVID-19) in relationship with iron metabolism” and we examined the potential properties of Growth and differentiation factor 15 (GDF15) as an emerging modulator of immunity in COVID-19. We commented new aspects of the biology of GDF15 and investigated the potential value of GDF15 as a biomarker. Is GDF15 a biomarker of the inflammatory process and oxidative stress state? Recently, it was reported that 1500 clinical trials related to COVID-19 have been registered, but none have yet found an optimal strategy. In these conditions, more clinical studies are needed before any of these agents can be considered antiviral agents.
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spelling pubmed-94779662022-09-16 GDF15 : A modulator of immunity and a predictive biomarker of cardiovascular events : A strategy in COVID-19 Rochette, Luc Dogon, Geoffrey Rigal, Eve Zeller, Marianne Vergely, Catherine Cottin, Yves Ann Cardiol Angeiol (Paris) Mise Au Point In the recently published manuscript entitled “GDF15 a rising modulator of immunity and a strategy in Coronavirus disease 2019 (COVID-19) in relationship with iron metabolism” and we examined the potential properties of Growth and differentiation factor 15 (GDF15) as an emerging modulator of immunity in COVID-19. We commented new aspects of the biology of GDF15 and investigated the potential value of GDF15 as a biomarker. Is GDF15 a biomarker of the inflammatory process and oxidative stress state? Recently, it was reported that 1500 clinical trials related to COVID-19 have been registered, but none have yet found an optimal strategy. In these conditions, more clinical studies are needed before any of these agents can be considered antiviral agents. Elsevier Masson SAS. 2023-02 2022-09-16 /pmc/articles/PMC9477966/ /pubmed/36163282 http://dx.doi.org/10.1016/j.ancard.2022.09.001 Text en © 2022 Elsevier Masson SAS. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Mise Au Point
Rochette, Luc
Dogon, Geoffrey
Rigal, Eve
Zeller, Marianne
Vergely, Catherine
Cottin, Yves
GDF15 : A modulator of immunity and a predictive biomarker of cardiovascular events : A strategy in COVID-19
title GDF15 : A modulator of immunity and a predictive biomarker of cardiovascular events : A strategy in COVID-19
title_full GDF15 : A modulator of immunity and a predictive biomarker of cardiovascular events : A strategy in COVID-19
title_fullStr GDF15 : A modulator of immunity and a predictive biomarker of cardiovascular events : A strategy in COVID-19
title_full_unstemmed GDF15 : A modulator of immunity and a predictive biomarker of cardiovascular events : A strategy in COVID-19
title_short GDF15 : A modulator of immunity and a predictive biomarker of cardiovascular events : A strategy in COVID-19
title_sort gdf15 : a modulator of immunity and a predictive biomarker of cardiovascular events : a strategy in covid-19
topic Mise Au Point
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9477966/
https://www.ncbi.nlm.nih.gov/pubmed/36163282
http://dx.doi.org/10.1016/j.ancard.2022.09.001
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