Cargando…

Blockage of Orai1-Nucleolin interaction meditated calcium influx attenuates breast cancer cells growth

As an important second messenger, calcium (Ca(2+)) regulates a wide variety of physiological processes. Disturbance of intracellular calcium homeostasis implicated in the occurrence of multiple types of diseases. Orai1 is the major player in mediating store-operated calcium entry (SOCE) and regulate...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gu, Chunming, Zhang, Wenhao, Yang, Enze, Gu, Congyou, Zhang, Zhaoyang, Ke, Jing, Wang, Xiong, Wu, Shengying, Li, Shan, Wu, Fuyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478099/ https://www.ncbi.nlm.nih.gov/pubmed/36109490 http://dx.doi.org/10.1038/s41389-022-00429-z

Ejemplares similares

Nucleolin Promotes Cisplatin Resistance in Cervical Cancer by the YB1-MDR1 Pathway
por: Ke, Jing, et al.
Publicado: (2021)

Crbn modulates calcium influx by regulating Orai1 during efferocytosis
por: Moon, Hyunji, et al.
Publicado: (2020)

Assessment of ORAI1-mediated basal calcium influx in mammary epithelial cells
por: Ross, Diana GF, et al.
Publicado: (2013)

AKT Regulation of ORAI1-Mediated Calcium Influx in Breast Cancer Cells
por: Bong, Alice Hui Li, et al.
Publicado: (2022)

Blockage of Store-Operated Ca(2+) Influx by Synta66 is Mediated by Direct Inhibition of the Ca(2+) Selective Orai1 Pore
por: Waldherr, Linda, et al.
Publicado: (2020)

Calcium Influx of Mast Cells Is Inhibited by Aptamers Targeting the First Extracellular Domain of Orai1
por: Sun, Renshan, et al.
Publicado: (2016)

The plasma membrane channel ORAI1 mediates detrimental calcium influx caused by endogenous oxidative stress
por: Henke, N, et al.
Publicado: (2013)

CRACking the structure of Orai: New work reveals the intramolecular properties of a store-operated, calcium influx channel
por: Braun, Andrew P.
Publicado: (2013)

STIM1-Orai1 interaction mediated calcium influx activation contributes to cardiac contractility of insulin-resistant rats
por: Durak, Aysegul, et al.
Publicado: (2022)

ORAI1-Regulated Gene Expression in Breast Cancer Cells: Roles for STIM1 Binding, Calcium Influx and Transcription Factor Translocation
por: Robitaille, Mélanie, et al.
Publicado: (2022)

Orai1 calcium channels in the vasculature
por: Beech, David J
Publicado: (2012)

Calcium, Orai1 and Epidermal Proliferation
por: Bikle, DD, et al.
Publicado: (2014)

Molecular understanding of calcium permeation through the open Orai channel
por: Liu, Xiaofen, et al.
Publicado: (2019)

X-Ray Causes mRNA Transcripts Change to Enhance Orai2-Mediated Ca(2+) Influx in Rat Brain Microvascular Endothelial Cells
por: Xu, Fangfang, et al.
Publicado: (2021)

Evaluation for the Genetic Association between Store-Operated Calcium Influx Pathway (STIM1 and ORAI1) and Human Hepatocellular Carcinoma in Patients with Chronic Hepatitis B Infection
por: Muhammad Irham, Lalu, et al.
Publicado: (2020)

Increased calcium influx in dystrophic muscle
Publicado: (1991)

Enhanced store-operated Ca(2+) influx and ORAI1 expression in ventricular fibroblasts from human failing heart
por: Ross, Gracious R., et al.
Publicado: (2017)

Orai1 and Orai3 in Combination with Stim1 Mediate the Majority of Store-operated Calcium Entry in Astrocytes
por: Kwon, Jea, et al.
Publicado: (2017)

Orai channel C-terminal peptides are key modulators of STlM-Orai coupling and calcium signal generation
por: Baraniak, James H., et al.
Publicado: (2021)

Targeting nucleolin to obstruct vasculature feeding with an intelligent DNA nanorobot
por: Li, Hua, et al.
Publicado: (2018)

STIM and Orai Mediated Regulation of Calcium Signaling in Age-Related Diseases
por: Collins, Helen E., et al.
Publicado: (2022)

Ovalicin attenuates atopic dermatitis symptoms by inhibiting IL-31 signaling and intracellular calcium influx
por: Hwang, Sung-Hyun, et al.
Publicado: (2021)

Extracellular Calcium Influx Pathways in Astrocyte Calcium Microdomain Physiology
por: Ahmadpour, Noushin, et al.
Publicado: (2021)

Orai1α and Orai1β support calcium entry and mammosphere formation in breast cancer stem cells
por: Jardin, Isaac, et al.
Publicado: (2023)

STIM and Orai1 Variants in Store-Operated Calcium Entry
por: Rosado, Juan A., et al.
Publicado: (2016)

Structures reveal opening of the store-operated calcium channel Orai
por: Hou, Xiaowei, et al.
Publicado: (2018)

ORAI Calcium Channels: Regulation, Function, Pharmacology, and Therapeutic Targets
por: Rubaiy, Hussein N.
Publicado: (2023)

Orai1 and Orai3 Mediate Store-Operated Calcium Entry Contributing to Neuronal Excitability in Dorsal Root Ganglion Neurons
por: Wei, Dongyu, et al.
Publicado: (2017)

Cryo-EM structure of the calcium release-activated calcium channel Orai in an open conformation
por: Hou, Xiaowei, et al.
Publicado: (2020)

Nobiletin attenuates neurotoxic mitochondrial calcium overload through K(+) influx and ΔΨ(m) across mitochondrial inner membrane
por: Lee, Ji Hyung, et al.
Publicado: (2018)

Calcium store refilling and STIM activation in STIM- and Orai-deficient cell lines
por: Zheng, Sisi, et al.
Publicado: (2018)

Similarities and Differences between the Orai1 Variants: Orai1α and Orai1β
por: Jardin, Isaac, et al.
Publicado: (2022)

Regulation of superoxide production in neutrophils: role of calcium influx
por: Bréchard, Sabrina, et al.
Publicado: (2008)

Calcium influx in internally dialyzed squid giant axons
Publicado: (1979)

Influx of calcium, strontium, and barium in presynaptic nerve endings
Publicado: (1982)

Altering calcium influx for selective destruction of breast tumor
por: Yu, Han-Gang, et al.
Publicado: (2017)

Altered Calcium Influx Pathways in Cancer-Associated Fibroblasts
por: Sadras, Francisco, et al.
Publicado: (2021)

Antibody-Mediated Targeting of the Orai1 Calcium Channel Inhibits T Cell Function
por: Cox, Jennifer H., et al.
Publicado: (2013)

Orai1 calcium channel inhibition prevents progression of chronic pancreatitis
por: Szabó, Viktória, et al.
Publicado: (2023)

Meditation Quality Matters: Effects of Loving-Kindness and Compassion Meditations on Subjective Well-being are Associated with Meditation Quality
por: Zeng, Xianglong, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_75s951pff4p6jst1f24sjjr8lg