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U-to-C RNA editing by synthetic PPR-DYW proteins in bacteria and human culture cells

Programmable RNA editing offers significant therapeutic potential for a wide range of genetic diseases. Currently, several deaminase enzymes, including ADAR and APOBEC, can perform programmable adenosine-to-inosine or cytidine-to-uridine RNA correction. However, enzymes to perform guanosine-to-adeno...

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Detalles Bibliográficos
Autores principales:	Ichinose, Mizuho, Kawabata, Masuyo, Akaiwa, Yumi, Shimajiri, Yasuka, Nakamura, Izumi, Tamai, Takayuki, Nakamura, Takahiro, Yagi, Yusuke, Gutmann, Bernard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478123/ https://www.ncbi.nlm.nih.gov/pubmed/36109586 http://dx.doi.org/10.1038/s42003-022-03927-3

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