Inhibition of UBA6 by inosine augments tumour immunogenicity and responses

Anti-cancer immunity and response to immune therapy is influenced by the metabolic states of the tumours. Immune checkpoint blockade therapy (ICB) is known to involve metabolic adaptation, however, the mechanism is not fully known. Here we show, by metabolic profiling of plasma samples from melanoma...

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Detalles Bibliográficos
Autores principales: Zhang, Lei, Jiang, Li, Yu, Liang, Li, Qin, Tian, Xiangjun, He, Jingquan, Zeng, Ling, Yang, Yuqin, Wang, Chaoran, Wei, Yuhan, Jiang, Xiaoyue, Li, Jing, Ge, Xiaolu, Gu, Qisheng, Li, Jikun, Wu, Di, Sadler, Anthony J., Yu, Di, Xu, Dakang, Gao, Yue, Yuan, Xiangliang, He, Baokun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478149/
https://www.ncbi.nlm.nih.gov/pubmed/36109526
http://dx.doi.org/10.1038/s41467-022-33116-z

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