Cargando…
Independent and combined associations of depressive symptoms and sleep disturbance with chronic pain in community-dwelling older adults
INTRODUCTION: There is limited evidence regarding whether depressive symptoms and sleep disturbance are independently or synergistically associated with chronic pain. OBJECTIVES: We investigated the independent and combined associations of depressive symptoms and sleep disturbance with chronic pain...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478345/ https://www.ncbi.nlm.nih.gov/pubmed/36128044 http://dx.doi.org/10.1097/PR9.0000000000001034 |
_version_ | 1784790550321299456 |
---|---|
author | Saito, Takafumi Chen, Tao Yatsugi, Harukaze Chu, Tianshu Liu, Xin Kishimoto, Hiro |
author_facet | Saito, Takafumi Chen, Tao Yatsugi, Harukaze Chu, Tianshu Liu, Xin Kishimoto, Hiro |
author_sort | Saito, Takafumi |
collection | PubMed |
description | INTRODUCTION: There is limited evidence regarding whether depressive symptoms and sleep disturbance are independently or synergistically associated with chronic pain. OBJECTIVES: We investigated the independent and combined associations of depressive symptoms and sleep disturbance with chronic pain and its severity (and the additive interactions) in community-dwelling older adults. METHODS: This cross-sectional study analyzed the data of 1374 individuals who were 65 to 75 year old, not in need of long-term care, and completed questionnaires assessing sociodemographic factors, depressive symptoms, sleep disturbance, and chronic pain. The severity of chronic pain was assessed based on pain intensity, pain distribution, and pain type. The participants' status of depressive symptoms and sleep disturbance were categorized in the following 4 groups: neither condition, depressive symptoms alone, sleep disturbance alone, and both conditions. RESULTS: Among the 1374 participants, 849 (61.8%) had chronic pain. The multivariable-adjusted odds ratios and 95% confidence intervals of the presence of chronic pain in those with depressive symptoms alone, sleep disturbance alone, and both conditions were 1.40 (0.97–2.03), 1.98 (1.41–2.78), and 2.12 (1.39–2.23), respectively, compared with the neither-condition group. Similar associations were observed for severe chronic pain. However, there were no significant additive interactions. In addition, only sleep disturbance was significantly associated with chronic pain, after adjusting for depressive symptoms. CONCLUSIONS: Our analyses did not reveal a synergistic effect of depressive symptoms and sleep disturbance on chronic pain and its severity, suggesting that most of the effects of depressive symptoms on chronic pain may be mediated by sleep disturbance. |
format | Online Article Text |
id | pubmed-9478345 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Wolters Kluwer |
record_format | MEDLINE/PubMed |
spelling | pubmed-94783452022-09-19 Independent and combined associations of depressive symptoms and sleep disturbance with chronic pain in community-dwelling older adults Saito, Takafumi Chen, Tao Yatsugi, Harukaze Chu, Tianshu Liu, Xin Kishimoto, Hiro Pain Rep General Section INTRODUCTION: There is limited evidence regarding whether depressive symptoms and sleep disturbance are independently or synergistically associated with chronic pain. OBJECTIVES: We investigated the independent and combined associations of depressive symptoms and sleep disturbance with chronic pain and its severity (and the additive interactions) in community-dwelling older adults. METHODS: This cross-sectional study analyzed the data of 1374 individuals who were 65 to 75 year old, not in need of long-term care, and completed questionnaires assessing sociodemographic factors, depressive symptoms, sleep disturbance, and chronic pain. The severity of chronic pain was assessed based on pain intensity, pain distribution, and pain type. The participants' status of depressive symptoms and sleep disturbance were categorized in the following 4 groups: neither condition, depressive symptoms alone, sleep disturbance alone, and both conditions. RESULTS: Among the 1374 participants, 849 (61.8%) had chronic pain. The multivariable-adjusted odds ratios and 95% confidence intervals of the presence of chronic pain in those with depressive symptoms alone, sleep disturbance alone, and both conditions were 1.40 (0.97–2.03), 1.98 (1.41–2.78), and 2.12 (1.39–2.23), respectively, compared with the neither-condition group. Similar associations were observed for severe chronic pain. However, there were no significant additive interactions. In addition, only sleep disturbance was significantly associated with chronic pain, after adjusting for depressive symptoms. CONCLUSIONS: Our analyses did not reveal a synergistic effect of depressive symptoms and sleep disturbance on chronic pain and its severity, suggesting that most of the effects of depressive symptoms on chronic pain may be mediated by sleep disturbance. Wolters Kluwer 2022-09-14 /pmc/articles/PMC9478345/ /pubmed/36128044 http://dx.doi.org/10.1097/PR9.0000000000001034 Text en Copyright © 2022 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The International Association for the Study of Pain. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. |
spellingShingle | General Section Saito, Takafumi Chen, Tao Yatsugi, Harukaze Chu, Tianshu Liu, Xin Kishimoto, Hiro Independent and combined associations of depressive symptoms and sleep disturbance with chronic pain in community-dwelling older adults |
title | Independent and combined associations of depressive symptoms and sleep disturbance with chronic pain in community-dwelling older adults |
title_full | Independent and combined associations of depressive symptoms and sleep disturbance with chronic pain in community-dwelling older adults |
title_fullStr | Independent and combined associations of depressive symptoms and sleep disturbance with chronic pain in community-dwelling older adults |
title_full_unstemmed | Independent and combined associations of depressive symptoms and sleep disturbance with chronic pain in community-dwelling older adults |
title_short | Independent and combined associations of depressive symptoms and sleep disturbance with chronic pain in community-dwelling older adults |
title_sort | independent and combined associations of depressive symptoms and sleep disturbance with chronic pain in community-dwelling older adults |
topic | General Section |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478345/ https://www.ncbi.nlm.nih.gov/pubmed/36128044 http://dx.doi.org/10.1097/PR9.0000000000001034 |
work_keys_str_mv | AT saitotakafumi independentandcombinedassociationsofdepressivesymptomsandsleepdisturbancewithchronicpainincommunitydwellingolderadults AT chentao independentandcombinedassociationsofdepressivesymptomsandsleepdisturbancewithchronicpainincommunitydwellingolderadults AT yatsugiharukaze independentandcombinedassociationsofdepressivesymptomsandsleepdisturbancewithchronicpainincommunitydwellingolderadults AT chutianshu independentandcombinedassociationsofdepressivesymptomsandsleepdisturbancewithchronicpainincommunitydwellingolderadults AT liuxin independentandcombinedassociationsofdepressivesymptomsandsleepdisturbancewithchronicpainincommunitydwellingolderadults AT kishimotohiro independentandcombinedassociationsofdepressivesymptomsandsleepdisturbancewithchronicpainincommunitydwellingolderadults |