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Functional inactivation of Plasmodium falciparum glycogen synthase kinase GSK3 modulates erythrocyte invasion and blocks gametocyte maturation

Malaria is responsible for hundreds of thousands of deaths every year. The lack of an effective vaccine and the global spread of multidrug resistant parasites hampers the fight against the disease and underlines the need for new antimalarial drugs. Central to the pathogenesis of malaria is the proli...

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Detalles Bibliográficos
Autores principales: Alder, Arne, Wilcke, Louisa, Pietsch, Emma, von Thien, Heidrun, Pazicky, Samuel, Löw, Christian, Mesen-Ramirez, Paolo, Bachmann, Anna, Burda, Paul-Christian, Kunick, Conrad, Sondermann, Holger, Wilson, Danny, Gilberger, Tim-Wolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478393/
https://www.ncbi.nlm.nih.gov/pubmed/35961464
http://dx.doi.org/10.1016/j.jbc.2022.102360