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Functional inactivation of Plasmodium falciparum glycogen synthase kinase GSK3 modulates erythrocyte invasion and blocks gametocyte maturation
Malaria is responsible for hundreds of thousands of deaths every year. The lack of an effective vaccine and the global spread of multidrug resistant parasites hampers the fight against the disease and underlines the need for new antimalarial drugs. Central to the pathogenesis of malaria is the proli...
Autores principales: | Alder, Arne, Wilcke, Louisa, Pietsch, Emma, von Thien, Heidrun, Pazicky, Samuel, Löw, Christian, Mesen-Ramirez, Paolo, Bachmann, Anna, Burda, Paul-Christian, Kunick, Conrad, Sondermann, Holger, Wilson, Danny, Gilberger, Tim-Wolf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478393/ https://www.ncbi.nlm.nih.gov/pubmed/35961464 http://dx.doi.org/10.1016/j.jbc.2022.102360 |
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