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Cyclin-dependent kinase-mediated phosphorylation and the negative regulatory domain of transcription factor B-Myb modulate its DNA binding
B-Myb is a highly conserved member of the vertebrate Myb family of transcription factors that plays a critical role in cell-cycle progression and proliferation. Myb proteins activate Myb-dependent promoters by interacting specifically with Myb-binding site (MBS) sequences using their DNA-binding dom...
Autores principales: | Wijeratne, Tilini U., Guiley, Keelan Z., Lee, Hsiau-Wei, Müller, Gerd A., Rubin, Seth M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478404/ https://www.ncbi.nlm.nih.gov/pubmed/35926712 http://dx.doi.org/10.1016/j.jbc.2022.102319 |
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