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Lysine demethylase KDM1A promotes cell growth via FKBP8–BCL2 axis in hepatocellular carcinoma

Advanced hepatocellular carcinoma (HCC) has a dismal prognosis. KDM1A (lysine demethylase 1A), overexpressed in multiple cancer types, is a lysine demethylase that targets both histone and nonhistone proteins. However, it is unclear how KDM1A expression affects HCC etiology. Here, we show that KDM1A...

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Detalles Bibliográficos
Autores principales:	Lv, Suli, Zhao, Xuefeng, Zhang, Erlei, Yan, Yingying, Ma, Xianyun, Li, Neng, Zou, Qingli, Sun, Lidong, Song, Tanjing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478407/ https://www.ncbi.nlm.nih.gov/pubmed/35970393 http://dx.doi.org/10.1016/j.jbc.2022.102374

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