Isocitrate dehydrogenase 3b is required for spermiogenesis but dispensable for retinal viability

Isocitrate dehydrogenase 3 (IDH3) is a key enzyme in the mitochondrial tricarboxylic acid (TCA) cycle, which catalyzes the decarboxylation of isocitrate into α-ketoglutarate and concurrently converts NAD(+) into NADH. Dysfunction of IDH3B, the β subunit of IDH3, has been previously correlated with r...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Siyan, Huang, Jiancheng, Xu, Rong, Wang, Yekai, Wan, Yiming, McNeel, Rachel, Parker, Edward, Kolson, Douglas, Yam, Michelle, Webb, Bradley, Zhao, Chen, Sigado, Jenna, Du, Jianhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478456/
https://www.ncbi.nlm.nih.gov/pubmed/35985423
http://dx.doi.org/10.1016/j.jbc.2022.102387

Ejemplares similares

Ejemplares similares