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Construction and characterization of a contagious ecthyma virus double-gene deletion strain and evaluation of its potential as a live-attenuated vaccine in goat

Contagious ecthyma is a highly contagious viral disease with zoonotic significance caused by orf virus (ORFV) that affects domestic, ruminants and humans. Live attenuated virus and attenuated tissue culture vaccines are widely used in the fight against ORFV, however, the conventional attenuated vacc...

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Detalles Bibliográficos
Autores principales: Zhu, Zhen, Qu, Guanggang, Du, Jige, Wang, Changjiang, Chen, Yong, Shen, Zhanning, Zhou, Zhiyu, Yin, Chunsheng, Chen, Xiaoyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478544/
https://www.ncbi.nlm.nih.gov/pubmed/36119021
http://dx.doi.org/10.3389/fimmu.2022.961287