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A fresh “slant” on modified Mitchell bladder neck reconstruction: A contemporary single-institution experience

INTRODUCTION: Patients with neurogenic urinary incontinence due to an incompetent outlet may be offered bladder neck reconstruction, but the quest for the perfect surgical-outlet procedure continues. Our aim was to characterize continence and complications after modified Mitchell urethral lengthenin...

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Autores principales: Bowen, Diana K., Cheng, Earl Y., Hirsch, Josephine, Huang, Jason, Meyer, Theresa, Rosoklija, Ilina, Chu, David I., Yerkes, Elizabeth B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478545/
https://www.ncbi.nlm.nih.gov/pubmed/36120660
http://dx.doi.org/10.3389/fped.2022.933481
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author Bowen, Diana K.
Cheng, Earl Y.
Hirsch, Josephine
Huang, Jason
Meyer, Theresa
Rosoklija, Ilina
Chu, David I.
Yerkes, Elizabeth B.
author_facet Bowen, Diana K.
Cheng, Earl Y.
Hirsch, Josephine
Huang, Jason
Meyer, Theresa
Rosoklija, Ilina
Chu, David I.
Yerkes, Elizabeth B.
author_sort Bowen, Diana K.
collection PubMed
description INTRODUCTION: Patients with neurogenic urinary incontinence due to an incompetent outlet may be offered bladder neck reconstruction, but the quest for the perfect surgical-outlet procedure continues. Our aim was to characterize continence and complications after modified Mitchell urethral lengthening/bladder neck reconstruction (MMBNR) with sling and to introduce a modification of exposure that facilitates subsequent steps of MMBNR. METHODS: A single-institution, retrospective cohort study of patients who underwent primary MMBNR between May 2011 and July 2019 was performed. Data on demographics, urodynamic testing, operative details, unanticipated events, continence, bladder changes, and additional procedures were collected. A 2013 modification that permits identification of the incompetent bladder neck prior to urethral unroofing was applied to the last 17 patients. The trigone and bladder neck are exposed via an oblique low anterolateral incision on the bladder. Ureteral reimplantation is not routinely performed. Focal incision of the endopelvic fascia after posterior plate creation limits breadth of blunt dissection for sling placement. Descriptive statistics were utilized. RESULTS: A total of 25 patients (13 females) had MMBNR with sling at a median age of 10 years [interquartile range (IQR) 8–11]. Bladder augmentation was performed concurrently in 14/25 (56%) patients. At a median of 5.0 (IQR 3.9–7.5) years follow-up after MMBNR, 9/11 (82%) without bladder augmentation and 13/14 (93%) with bladder augmentation had no leakage per urethra during the day without further continence procedures. Of the three patients with persistent incontinence, two achieved continence with bladder wall Botox injection (overall continence 24/25, 96%). New and recurrent vesicoureteral reflux was noted in five patients and one patient, respectively. Two patients required subsequent bladder augmentation for pressures and one other will likely require it. None have required bladder neck closure or revision. CONCLUSION: MMBNR with sling provides promising continence per urethra in neurogenic bladder with low need for secondary continence procedures. Ongoing modifications may achieve elusive total continence.
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spelling pubmed-94785452022-09-17 A fresh “slant” on modified Mitchell bladder neck reconstruction: A contemporary single-institution experience Bowen, Diana K. Cheng, Earl Y. Hirsch, Josephine Huang, Jason Meyer, Theresa Rosoklija, Ilina Chu, David I. Yerkes, Elizabeth B. Front Pediatr Pediatrics INTRODUCTION: Patients with neurogenic urinary incontinence due to an incompetent outlet may be offered bladder neck reconstruction, but the quest for the perfect surgical-outlet procedure continues. Our aim was to characterize continence and complications after modified Mitchell urethral lengthening/bladder neck reconstruction (MMBNR) with sling and to introduce a modification of exposure that facilitates subsequent steps of MMBNR. METHODS: A single-institution, retrospective cohort study of patients who underwent primary MMBNR between May 2011 and July 2019 was performed. Data on demographics, urodynamic testing, operative details, unanticipated events, continence, bladder changes, and additional procedures were collected. A 2013 modification that permits identification of the incompetent bladder neck prior to urethral unroofing was applied to the last 17 patients. The trigone and bladder neck are exposed via an oblique low anterolateral incision on the bladder. Ureteral reimplantation is not routinely performed. Focal incision of the endopelvic fascia after posterior plate creation limits breadth of blunt dissection for sling placement. Descriptive statistics were utilized. RESULTS: A total of 25 patients (13 females) had MMBNR with sling at a median age of 10 years [interquartile range (IQR) 8–11]. Bladder augmentation was performed concurrently in 14/25 (56%) patients. At a median of 5.0 (IQR 3.9–7.5) years follow-up after MMBNR, 9/11 (82%) without bladder augmentation and 13/14 (93%) with bladder augmentation had no leakage per urethra during the day without further continence procedures. Of the three patients with persistent incontinence, two achieved continence with bladder wall Botox injection (overall continence 24/25, 96%). New and recurrent vesicoureteral reflux was noted in five patients and one patient, respectively. Two patients required subsequent bladder augmentation for pressures and one other will likely require it. None have required bladder neck closure or revision. CONCLUSION: MMBNR with sling provides promising continence per urethra in neurogenic bladder with low need for secondary continence procedures. Ongoing modifications may achieve elusive total continence. Frontiers Media S.A. 2022-09-02 /pmc/articles/PMC9478545/ /pubmed/36120660 http://dx.doi.org/10.3389/fped.2022.933481 Text en Copyright © 2022 Bowen, Cheng, Hirsch, Huang, Meyer, Rosoklija, Chu and Yerkes. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Bowen, Diana K.
Cheng, Earl Y.
Hirsch, Josephine
Huang, Jason
Meyer, Theresa
Rosoklija, Ilina
Chu, David I.
Yerkes, Elizabeth B.
A fresh “slant” on modified Mitchell bladder neck reconstruction: A contemporary single-institution experience
title A fresh “slant” on modified Mitchell bladder neck reconstruction: A contemporary single-institution experience
title_full A fresh “slant” on modified Mitchell bladder neck reconstruction: A contemporary single-institution experience
title_fullStr A fresh “slant” on modified Mitchell bladder neck reconstruction: A contemporary single-institution experience
title_full_unstemmed A fresh “slant” on modified Mitchell bladder neck reconstruction: A contemporary single-institution experience
title_short A fresh “slant” on modified Mitchell bladder neck reconstruction: A contemporary single-institution experience
title_sort fresh “slant” on modified mitchell bladder neck reconstruction: a contemporary single-institution experience
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478545/
https://www.ncbi.nlm.nih.gov/pubmed/36120660
http://dx.doi.org/10.3389/fped.2022.933481
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