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Mechanism by which T7 bacteriophage protein Gp1.2 inhibits Escherichia coli dGTPase

Levels of the cellular dNTPs, the direct precursors for DNA synthesis, are important for DNA replication fidelity, cell cycle control, and resistance against viruses. Escherichia coli encodes a dGTPase (2′-deoxyguanosine-5′-triphosphate [dGTP] triphosphohydrolase [dGTPase]; dgt gene, Dgt) that estab...

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Detalles Bibliográficos
Autores principales:	Klemm, Bradley P., Singh, Deepa, Smith, Cassandra E., Hsu, Allen L., Dillard, Lucas B., Krahn, Juno M., London, Robert E., Mueller, Geoffrey A., Borgnia, Mario J., Schaaper, Roel M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478638/ https://www.ncbi.nlm.nih.gov/pubmed/36067314 http://dx.doi.org/10.1073/pnas.2123092119

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