Inferring the initiation and development of myeloproliferative neoplasms

The developmental history of blood cancer begins with mutation acquisition and the resulting malignant clone expansion. The two most prevalent driver mutations found in myeloproliferative neoplasms—JAK2(V617F) and CALR(m)—occur in hematopoietic stem cells, which are highly complex to observe in vivo...

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Detalles Bibliográficos
Autores principales: Hermange, Gurvan, Rakotonirainy, Alicia, Bentriou, Mahmoud, Tisserand, Amandine, El-Khoury, Mira, Girodon, François, Marzac, Christophe, Vainchenker, William, Plo, Isabelle, Cournède, Paul-Henry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478641/
https://www.ncbi.nlm.nih.gov/pubmed/36083966
http://dx.doi.org/10.1073/pnas.2120374119

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