ISL1 is necessary for auditory neuron development and contributes toward tonotopic organization

A cardinal feature of the auditory pathway is frequency selectivity, represented in a tonotopic map from the cochlea to the cortex. The molecular determinants of the auditory frequency map are unknown. Here, we discovered that the transcription factor ISL1 regulates the molecular and cellular featur...

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Detalles Bibliográficos
Autores principales: Filova, Iva, Pysanenko, Kateryna, Tavakoli, Mitra, Vochyanova, Simona, Dvorakova, Martina, Bohuslavova, Romana, Smolik, Ondrej, Fabriciova, Valeria, Hrabalova, Petra, Benesova, Sarka, Valihrach, Lukas, Cerny, Jiri, Yamoah, Ebenezer N., Syka, Josef, Fritzsch, Bernd, Pavlinkova, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478650/
https://www.ncbi.nlm.nih.gov/pubmed/36074819
http://dx.doi.org/10.1073/pnas.2207433119

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