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IRF3 inhibits nuclear translocation of NF-κB to prevent viral inflammation

Interferon (IFN) regulatory factor 3 (IRF3) is a transcription factor activated by phosphorylation in the cytoplasm of a virus-infected cell; by translocating to the nucleus, it induces transcription of IFN-β and other antiviral genes. We have previously reported IRF3 can also be activated, as a pro...

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Detalles Bibliográficos
Autores principales:	Popli, Sonam, Chakravarty, Sukanya, Fan, Shumin, Glanz, Anna, Aras, Siddhesh, Nagy, Laura E., Sen, Ganes C., Chakravarti, Ritu, Chattopadhyay, Saurabh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2022
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478676/ https://www.ncbi.nlm.nih.gov/pubmed/36067309 http://dx.doi.org/10.1073/pnas.2121385119

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