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Precise exogenous insertion and sequence replacements in poplar by simultaneous HDR overexpression and NHEJ suppression using CRISPR-Cas9

CRISPR-mediated genome editing has become a powerful tool for the genetic modification of biological traits. However, developing an efficient, site-specific, gene knock-in system based on homology-directed DNA repair (HDR) remains a significant challenge in plants, especially in woody species like p...

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Detalles Bibliográficos
Autores principales: Movahedi, Ali, Wei, Hui, Zhou, Xiaohong, Fountain, Jake C, Chen, Zhong-Hua, Mu, Zhiying, Sun, Weibo, Zhang, Jiaxin, Li, Dawei, Guo, Baozhu, Varshney, Rajeev K, Yang, Liming, Zhuge, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478684/
https://www.ncbi.nlm.nih.gov/pubmed/36133672
http://dx.doi.org/10.1093/hr/uhac154

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