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Eight gene mutation-based polygenic hazard score as a potential predictor for immune checkpoint inhibitor therapy outcome in metastatic melanoma

Background: Immune checkpoint inhibitor (ICI) therapies have revolutionized the treatment of metastatic cutaneous melanoma, but have only benefitted a subset of them. Gene mutations were reported to impact the ICI therapy outcomes in metastatic melanoma but have not been fully investigated. Hence, w...

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Detalles Bibliográficos
Autores principales:	Zhao, Liqin, Luo, Ting, Jiang, Jinling, Wu, Junwei, Zhang, Xiaowei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478752/ https://www.ncbi.nlm.nih.gov/pubmed/36120536 http://dx.doi.org/10.3389/fmolb.2022.1001792

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