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The nepenthesin insert in the Plasmodium falciparum aspartic protease plasmepsin V is necessary for enzyme function

Plasmepsin V (PM V) is a pepsin-like aspartic protease essential for growth of the malarial parasite Plasmodium falciparum. Previous work has shown PM V to be an endoplasmic reticulum–resident protease that processes parasite proteins destined for export into the host cell. Depletion or inhibition o...

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Detalles Bibliográficos
Autores principales:	Polino, Alexander J., Miller, Justin J., Bhakat, Soumendranath, Mukherjee, Sumit, Bobba, Suhas, Bowman, Gregory R., Goldberg, Daniel E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478907/ https://www.ncbi.nlm.nih.gov/pubmed/35952758 http://dx.doi.org/10.1016/j.jbc.2022.102355

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