Cargando…

Characterization and comparison of novel adjuvants for a prefusion clamped MERS vaccine

Various chemical adjuvants are available to augment immune responses to non-replicative, subunit vaccines. Optimized adjuvant selection can ensure that vaccine-induced immune responses protect against the diversity of pathogen-associated infection routes, mechanisms of infectious spread, and pathway...

Descripción completa

Detalles Bibliográficos
Autores principales:	O’Donnell, Jake S., Isaacs, Ariel, Jakob, Virginie, Lebas, Celia, Barnes, James B., Reading, Patrick C., Young, Paul R., Watterson, Daniel, Dubois, Patrice M., Collin, Nicolas, Chappell, Keith J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478912/ https://www.ncbi.nlm.nih.gov/pubmed/36119058 http://dx.doi.org/10.3389/fimmu.2022.976968

Ejemplares similares

Adjuvant Selection for Influenza and RSV Prefusion Subunit Vaccines
por: Isaacs, Ariel, et al.
Publicado: (2021)

Development of molecular clamp stabilized hemagglutinin vaccines for Influenza A viruses
por: McMillan, Christopher L. D., et al.
Publicado: (2021)

Author Correction: Development of molecular clamp stabilized hemagglutinin vaccines for Influenza A viruses
por: McMillan, Christopher L. D., et al.
Publicado: (2022)

Chronic SARS-CoV-2, a Cause of Post-acute COVID-19 Sequelae (Long-COVID)?
por: O’Donnell, Jake S., et al.
Publicado: (2021)

The ring-type polymerase sliding clamp family
por: Bruck, Irina, et al.
Publicado: (2001)

DNA is loaded through the 9-1-1 DNA checkpoint clamp in the opposite direction of the PCNA clamp
por: Zheng, Fengwei, et al.
Publicado: (2022)

Architecture of the SARS coronavirus prefusion spike
por: Beniac, Daniel R, et al.
Publicado: (2006)

A Phase 1/2 Study of a Respiratory Syncytial Virus Prefusion F Vaccine With and Without Adjuvant in Healthy Older Adults
por: Baber, James, et al.
Publicado: (2022)

Immunogenicity of an AS01-adjuvanted respiratory syncytial virus prefusion F (RSVPreF3) vaccine in animal models
por: Bouzya, Badiaa, et al.
Publicado: (2023)

Unexpected new insights into DNA clamp loaders: Eukaryotic clamp loaders contain a second DNA site for recessed 5′ ends that facilitates repair and signals DNA damage
por: Li, Huilin, et al.
Publicado: (2022)

Clamp loader ATPases and the evolution of DNA replication machinery
por: Kelch, Brian A, et al.
Publicado: (2012)

Long-term safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2 in adults aged 18–55 years or ≥56 years: 12-month results from a randomised, double-blind, placebo-controlled, phase 1 trial
por: Chappell, Keith J., et al.
Publicado: (2023)

Conserved residues in the δ subunit help the E. coli clamp loader, γ complex, target primer-template DNA for clamp assembly
por: Chen, Siying, et al.
Publicado: (2008)

Safety and immunogenicity of an MF59-adjuvanted spike glycoprotein-clamp vaccine for SARS-CoV-2: a randomised, double-blind, placebo-controlled, phase 1 trial
por: Chappell, Keith J, et al.
Publicado: (2021)

The Escherichia coli Clamp Loader Can Actively Pry Open the β-Sliding Clamp
por: Paschall, Christopher O., et al.
Publicado: (2011)

Involvement of the β Clamp in Methyl-directed Mismatch Repair in Vitro
por: Pluciennik, Anna, et al.
Publicado: (2009)

Development of recombinant COVID-19 vaccine based on CHO-produced, prefusion spike trimer and alum/CpG adjuvants
por: Liu, Haitao, et al.
Publicado: (2021)

HRSV prefusion-F protein with Adju-Phos adjuvant induces long-lasting Th2-biased immunity in mice
por: Li, Hai, et al.
Publicado: (2022)

Rapid Response Subunit Vaccine Design in the Absence of Structural Information
por: Wijesundara, Danushka K., et al.
Publicado: (2020)

High-throughput identification of prefusion-stabilizing mutations in SARS-CoV-2 spike
por: Tan, Timothy J.C., et al.
Publicado: (2022)

High-throughput identification of prefusion-stabilizing mutations in SARS-CoV-2 spike
por: Tan, Timothy J. C., et al.
Publicado: (2023)

Generation of a monoclonal antibody reactive to prefusion myocytes
por: Kurisaki, Tomohiro, et al.
Publicado: (2011)

Transient opening of trimeric prefusion RSV F proteins
por: Gilman, Morgan S. A., et al.
Publicado: (2019)

The prefusion structure of herpes simplex virus glycoprotein B
por: Vollmer, B., et al.
Publicado: (2020)

Prefused lysosomes cluster on autophagosomes regulated by VAMP8
por: Chen, Qixin, et al.
Publicado: (2021)

Analysis of the role of PCNA-DNA contacts during clamp loading
por: McNally, Randall, et al.
Publicado: (2010)

Structure of eukaryotic DNA polymerase δ bound to the PCNA clamp while encircling DNA
por: Zheng, Fengwei, et al.
Publicado: (2020)

Structure and immune recognition of trimeric prefusion HIV-1 Env
por: Pancera, Marie, et al.
Publicado: (2014)

Crystal structure of the prefusion surface glycoprotein of the prototypic arenavirus LCMV
por: Hastie, Kathryn M., et al.
Publicado: (2016)

Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike
por: Huo, Jiandong, et al.
Publicado: (2020)

Structure-Based Design of Prefusion-Stabilized Filovirus Glycoprotein Trimers
por: Rutten, Lucy, et al.
Publicado: (2020)

Fighting Ebola: A Window for Vaccine Re-evaluation?
por: Chappell, Keith J., et al.
Publicado: (2017)

Induction of high titred, non-neutralising antibodies by self-adjuvanting peptide epitopes derived from the respiratory syncytial virus fusion protein
por: Jaberolansar, Noushin, et al.
Publicado: (2017)

Development of CpG-adjuvanted stable prefusion SARS-CoV-2 spike antigen as a subunit vaccine against COVID-19
por: Kuo, Tsun-Yung, et al.
Publicado: (2020)

Preclinical development of a molecular clamp‐stabilised subunit vaccine for severe acute respiratory syndrome coronavirus 2
por: Watterson, Daniel, et al.
Publicado: (2021)

Crystal structure of a DNA polymerase sliding clamp from a Gram-positive bacterium
por: Argiriadi, Maria A, et al.
Publicado: (2006)

Immunological studies of the embryonic muscle cell surface. Antiserum to the prefusion myoblast
Publicado: (1979)

Dynamics of SARS-coronavirus HR2 domain in the prefusion and transition states
por: McReynolds, Susanna, et al.
Publicado: (2009)

Protection of calves by a prefusion-stabilized bovine RSV F vaccine
por: Zhang, Baoshan, et al.
Publicado: (2017)

Structure-based design of prefusion-stabilized human metapneumovirus fusion proteins
por: Hsieh, Ching-Lin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_gp1l8i1c7srmfn1sdnn2ai29nd