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DNA methyltransferases are complementary in maintaining DNA methylation in embryonic stem cells

ZFP57 and ZFP445 maintain genomic imprinting in mouse embryos. We found DNA methylation was lost at most examined imprinting control regions (ICRs) in mouse Zfp57 mutant ES cells, which could not be prevented by the elimination of three TET proteins. To elucidate methylation maintenance mechanisms,...

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Detalles Bibliográficos
Autores principales:	Liu, Yuhan, Xu, Zhen, Shi, Jiajia, Zhang, Yu, Yang, Shuting, Chen, Qian, Song, Chenglin, Geng, Shuhui, Li, Qing, Li, Jinsong, Xu, Guo-Liang, Xie, Wei, Lin, Haodong, Li, Xiajun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478929/ https://www.ncbi.nlm.nih.gov/pubmed/36117996 http://dx.doi.org/10.1016/j.isci.2022.105003

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