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Costimulation blockade and Tregs in solid organ transplantation

Regulatory T cells (Tregs) play a critical role in maintaining self-tolerance and in containing allo-immune responses in the context of transplantation. Recent advances yielded the approval of the first pharmaceutical costimulation blockers (abatacept and belatacept), with more of them in the pipeli...

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Detalles Bibliográficos
Autores principales:	Muckenhuber, Moritz, Wekerle, Thomas, Schwarz, Christoph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9478950/ https://www.ncbi.nlm.nih.gov/pubmed/36119115 http://dx.doi.org/10.3389/fimmu.2022.969633

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