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Beyond targeting amplified MDM2 and CDK4 in well differentiated and dedifferentiated liposarcomas: From promise and clinical applications towards identification of progression drivers

Well differentiated and dedifferentiated liposarcomas (WDLPS and DDLPS) are tumors of the adipose tissue poorly responsive to conventional cytotoxic chemotherapy which currently remains the standard-of-care. The dismal prognosis of the DDLPS subtype indicates an urgent need to identify new therapeut...

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Detalles Bibliográficos
Autores principales:	Cassinelli, Giuliana, Pasquali, Sandro, Lanzi, Cinzia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479065/ https://www.ncbi.nlm.nih.gov/pubmed/36119484 http://dx.doi.org/10.3389/fonc.2022.965261

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