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Hemin-incorporating DNA nanozyme enabling catalytic oxygenation and GSH depletion for enhanced photodynamic therapy and synergistic tumor ferroptosis

Photodynamic therapy (PDT) has emerged as a promising tumor treatment method via light-triggered generation of reactive oxygen species (ROS) to kill tumor cells. However, the efficacy of PDT is usually restricted by several biological limitations, including hypoxia, excess glutathione (GSH) neutrali...

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Detalles Bibliográficos
Autores principales: Xiao, Xiaoxiong, Chen, Min, Zhang, Yuchen, Li, Liang, Peng, Ying, Zhou, Wenhu, Li, Junyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479271/
https://www.ncbi.nlm.nih.gov/pubmed/36109814
http://dx.doi.org/10.1186/s12951-022-01617-0