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Hemin-incorporating DNA nanozyme enabling catalytic oxygenation and GSH depletion for enhanced photodynamic therapy and synergistic tumor ferroptosis
Photodynamic therapy (PDT) has emerged as a promising tumor treatment method via light-triggered generation of reactive oxygen species (ROS) to kill tumor cells. However, the efficacy of PDT is usually restricted by several biological limitations, including hypoxia, excess glutathione (GSH) neutrali...
Autores principales: | Xiao, Xiaoxiong, Chen, Min, Zhang, Yuchen, Li, Liang, Peng, Ying, Zhou, Wenhu, Li, Junyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479271/ https://www.ncbi.nlm.nih.gov/pubmed/36109814 http://dx.doi.org/10.1186/s12951-022-01617-0 |
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