Cargando…

Targeting therapy and tumor microenvironment remodeling of triple-negative breast cancer by ginsenoside Rg3 based liposomes

The chemotherapy effect of docetaxel (DTX) against triple-negative breast cancer (TNBC) remains mediocre and limited when encapsulated in conventional cholesterol liposomes, mainly ascribed to poor penetration and immunosuppressive tumor microenvironment (TME) caused by tumor stroma cells, especiall...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xia, Jiaxuan, Zhang, Shuya, Zhang, Ru, Wang, Anni, Zhu, Ying, Dong, Meichen, Ma, Shaojie, Hong, Chao, Liu, Shengyao, Wang, Dan, Wang, Jianxin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479350/ https://www.ncbi.nlm.nih.gov/pubmed/36109762 http://dx.doi.org/10.1186/s12951-022-01623-2

Ejemplares similares

Paclitaxel-loaded ginsenoside Rg3 liposomes for drug-resistant cancer therapy by dual targeting of the tumor microenvironment and cancer cells
por: Zhu, Ying, et al.
Publicado: (2022)

Versatile ginsenoside Rg3 liposomes inhibit tumor metastasis by capturing circulating tumor cells and destroying metastatic niches
por: Xia, Jiaxuan, et al.
Publicado: (2022)

Effect of the structure of ginsenosides on the in vivo fate of their liposomes
por: Chen, Chen, et al.
Publicado: (2022)

Novel ginsenoside-based multifunctional liposomal delivery system for combination therapy of gastric cancer
por: Hong, Chao, et al.
Publicado: (2019)

Stereoselective Anti-Cancer Activities of Ginsenoside Rg3 on Triple Negative Breast Cancer Cell Models
por: Nakhjavani, Maryam, et al.
Publicado: (2019)

One Stone Four Birds: A Novel Liposomal Delivery System Multi-functionalized with Ginsenoside Rh2 for Tumor Targeting Therapy
por: Hong, Chao, et al.
Publicado: (2020)

20(S)-Ginsenoside Rg3 Promotes HeLa Cell Apoptosis by Regulating Autophagy
por: Bian, Shuai, et al.
Publicado: (2019)

The effects and mechanism of ginsenoside Rg1 on myocardial remodeling in an animal model of chronic thromboembolic pulmonary hypertension
por: Li, Chang-yi, et al.
Publicado: (2013)

Anti-Cancer Effects of an Optimised Combination of Ginsenoside Rg3 Epimers on Triple Negative Breast Cancer Models
por: Nakhjavani, Maryam, et al.
Publicado: (2021)

The positive effects of Ginsenoside Rg1 upon the hematopoietic microenvironment in a D-Galactose-induced aged rat model
por: Hu, Wenxu, et al.
Publicado: (2015)

Protective effect and mechanism of ginsenoside Rg2 on atherosclerosis
por: Xue, Qianqian, et al.
Publicado: (2023)

Therapeutic effect of various ginsenosides on rheumatoid arthritis
por: Zhang, Meng, et al.
Publicado: (2021)

Simultaneous quantification of ginsenoside Rg1 and its metabolites by HPLC–MS/MS: Rg1 excretion in rat bile, urine and feces
por: He, Chiyu, et al.
Publicado: (2016)

Anti-Angiogenic Properties of Ginsenoside Rg3
por: Nakhjavani, Maryam, et al.
Publicado: (2020)

Pharmacological activities of ginsenoside Rg5 (Review)
por: Liu, Ming-Yang, et al.
Publicado: (2021)

A systematic review and meta-analysis of Ginsenoside-Rg1 (G-Rg1) in experimental ischemic stroke
por: Xie, Cheng-long, et al.
Publicado: (2015)

Comparative Pharmacokinetics of Ginsenoside Rg(3) and Ginsenoside Rh(2) after Oral Administration of Ginsenoside Rg(3) in Normal and Walker 256 Tumor-bearing Rats
por: Fan, He, et al.
Publicado: (2016)

Protective effect of ginsenoside Rg1 on lidocaine-induced apoptosis
por: LI, HUI, et al.
Publicado: (2014)

In Vitro/In Vivo Metabolism of Ginsenoside Rg5 in Rat Using Ultra-Performance Liquid Chromatography/Quadrupole-Time-of-Flight Mass Spectrometry
por: Hong, Chao, et al.
Publicado: (2018)

Ginsenoside Rg3 inhibits the biological activity of SGC‐7901
por: Yang, Qing, et al.
Publicado: (2020)

Ginsenoside Rg1 Delays Chronological Aging in a Yeast Model via CDC19- and SDH2-Mediated Cellular Metabolism
por: Wang, Siming, et al.
Publicado: (2023)

Polymer-Based Wound Dressings Loaded with Ginsenoside Rg3
por: Yang, Jiali, et al.
Publicado: (2023)

Molecular signaling of ginsenosides Rb1, Rg1, and Rg3 and their mode of actions
por: Mohanan, Padmanaban, et al.
Publicado: (2018)

Ginsenoside Rg2 Attenuated Trastuzumab-Induced Cardiotoxicity in Rats
por: Liu, Guang, et al.
Publicado: (2022)

Ginsenoside Rg1 Ameliorates Behavioral Abnormalities and Modulates the Hippocampal Proteomic Change in Triple Transgenic Mice of Alzheimer's Disease
por: Nie, Lulin, et al.
Publicado: (2017)

Anti-adipogenic Effects and Mechanisms of Ginsenoside Rg3 in Pre-adipocytes and Obese Mice
por: Zhang, Longyun, et al.
Publicado: (2017)

Relationship Between Ginsenoside Rg3 and Metabolic Syndrome
por: Lee, Hyunji, et al.
Publicado: (2020)

Novel Antidepressant Mechanism of Ginsenoside Rg1 in Regulating the Dysfunction of the Glutamatergic System in Astrocytes
por: Zhang, Ningning, et al.
Publicado: (2022)

An improved method for the preparation of Ginsenoside Rg5 from ginseng fibrous root powder
por: Guo, Dan-dan, et al.
Publicado: (2019)

Ginsenoside Rg1 Induces Apoptotic Cell Death in Triple-Negative Breast Cancer Cell Lines and Prevents Carcinogen-Induced Breast Tumorigenesis in Sprague Dawley Rats
por: Chu, Yan, et al.
Publicado: (2020)

Ginsenoside-Rg5 induces apoptosis and DNA damage in human cervical cancer cells
por: LIANG, LI-DAN, et al.
Publicado: (2015)

Evaluation of the gastroprotective effects of 20 (S)-ginsenoside Rg3 on gastric ulcer models in mice
por: Zhang, Kai, et al.
Publicado: (2019)

Kinetic study for the optimization of ginsenoside Rg3 production by heat treatment of ginsenoside Rb1
por: Vo, Hoang Tung, et al.
Publicado: (2015)

Effects of ginsenoside Rg3 on epigenetic modification in ovarian cancer cells
por: Zhao, Lingqin, et al.
Publicado: (2019)

Fabrication of Ginsenoside-Based Nanodrugs for Enhanced Antitumor Efficacy on Triple-Negative Breast Cancer
por: Zuo, Shuting, et al.
Publicado: (2022)

Ginsenoside Rg1 attenuates liver injury induced by D-galactose in mice
por: Xiao, Ming-He, et al.
Publicado: (2018)

Genomic expression profiling and bioinformatics analysis on diabetic nephrology with ginsenoside Rg3
por: Wang, Juan, et al.
Publicado: (2016)

Ginsenoside Rg1 promotes lymphatic drainage and improves chronic inflammatory arthritis
por: Hou, Tong, et al.
Publicado: (2020)

Ginsenoside Rg1 and 20(S)-Rg3 Induce IgA Production by Mouse B Cells
por: Park, Ha-Yan, et al.
Publicado: (2015)

Ginsenoside Rg1 ameliorates Alzheimer's disease pathology via restoring mitophagy
por: Wang, Ni, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_c4s65381ijut7ollf4uvvn7ici