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Emergence of genetically linked vaccine-originated poliovirus type 2 in the absence of oral polio vaccine, Jerusalem, April to July 2022
We report an emergence and increase in poliovirus type 2 detection via routine wastewater surveillance in three non-overlapping regions in the Jerusalem region, Israel, between April and July 2022. Sequencing showed genetic linkage among isolates and accumulation of mutations over time, with two iso...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Centre for Disease Prevention and Control (ECDC)
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479469/ https://www.ncbi.nlm.nih.gov/pubmed/36111556 http://dx.doi.org/10.2807/1560-7917.ES.2022.27.37.2200694 |
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author | Zuckerman, Neta S Bar-Or, Itay Sofer, Danit Bucris, Efrat Morad, Hagar Shulman, Lester M Levi, Nofar Weiss, Leah Aguvaev, Irina Cohen, Zvi Kestin, Klil Vasserman, Rinat Elul, Michal Fratty, Ilana S Geva, Miranda Wax, Marina Erster, Oran Yishai, Ruth Hecht-Sagie, Lior Alroy-Preis, Sharon Mendelson, Ella Weil, Merav |
author_facet | Zuckerman, Neta S Bar-Or, Itay Sofer, Danit Bucris, Efrat Morad, Hagar Shulman, Lester M Levi, Nofar Weiss, Leah Aguvaev, Irina Cohen, Zvi Kestin, Klil Vasserman, Rinat Elul, Michal Fratty, Ilana S Geva, Miranda Wax, Marina Erster, Oran Yishai, Ruth Hecht-Sagie, Lior Alroy-Preis, Sharon Mendelson, Ella Weil, Merav |
author_sort | Zuckerman, Neta S |
collection | PubMed |
description | We report an emergence and increase in poliovirus type 2 detection via routine wastewater surveillance in three non-overlapping regions in the Jerusalem region, Israel, between April and July 2022. Sequencing showed genetic linkage among isolates and accumulation of mutations over time, with two isolates defined as vaccine-derived polioviruses (VDPV). This demonstrates the emergence and potential circulation of type 2 VDPV in a high-income country with high vaccine coverage and underscores the importance of routine wastewater surveillance during the polio eradication. |
format | Online Article Text |
id | pubmed-9479469 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | European Centre for Disease Prevention and Control (ECDC) |
record_format | MEDLINE/PubMed |
spelling | pubmed-94794692022-10-03 Emergence of genetically linked vaccine-originated poliovirus type 2 in the absence of oral polio vaccine, Jerusalem, April to July 2022 Zuckerman, Neta S Bar-Or, Itay Sofer, Danit Bucris, Efrat Morad, Hagar Shulman, Lester M Levi, Nofar Weiss, Leah Aguvaev, Irina Cohen, Zvi Kestin, Klil Vasserman, Rinat Elul, Michal Fratty, Ilana S Geva, Miranda Wax, Marina Erster, Oran Yishai, Ruth Hecht-Sagie, Lior Alroy-Preis, Sharon Mendelson, Ella Weil, Merav Euro Surveill Rapid Communication We report an emergence and increase in poliovirus type 2 detection via routine wastewater surveillance in three non-overlapping regions in the Jerusalem region, Israel, between April and July 2022. Sequencing showed genetic linkage among isolates and accumulation of mutations over time, with two isolates defined as vaccine-derived polioviruses (VDPV). This demonstrates the emergence and potential circulation of type 2 VDPV in a high-income country with high vaccine coverage and underscores the importance of routine wastewater surveillance during the polio eradication. European Centre for Disease Prevention and Control (ECDC) 2022-09-15 /pmc/articles/PMC9479469/ /pubmed/36111556 http://dx.doi.org/10.2807/1560-7917.ES.2022.27.37.2200694 Text en This article is copyright of the authors or their affiliated institutions, 2022. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made. |
spellingShingle | Rapid Communication Zuckerman, Neta S Bar-Or, Itay Sofer, Danit Bucris, Efrat Morad, Hagar Shulman, Lester M Levi, Nofar Weiss, Leah Aguvaev, Irina Cohen, Zvi Kestin, Klil Vasserman, Rinat Elul, Michal Fratty, Ilana S Geva, Miranda Wax, Marina Erster, Oran Yishai, Ruth Hecht-Sagie, Lior Alroy-Preis, Sharon Mendelson, Ella Weil, Merav Emergence of genetically linked vaccine-originated poliovirus type 2 in the absence of oral polio vaccine, Jerusalem, April to July 2022 |
title | Emergence of genetically linked vaccine-originated poliovirus type 2 in the absence of oral polio vaccine, Jerusalem, April to July 2022 |
title_full | Emergence of genetically linked vaccine-originated poliovirus type 2 in the absence of oral polio vaccine, Jerusalem, April to July 2022 |
title_fullStr | Emergence of genetically linked vaccine-originated poliovirus type 2 in the absence of oral polio vaccine, Jerusalem, April to July 2022 |
title_full_unstemmed | Emergence of genetically linked vaccine-originated poliovirus type 2 in the absence of oral polio vaccine, Jerusalem, April to July 2022 |
title_short | Emergence of genetically linked vaccine-originated poliovirus type 2 in the absence of oral polio vaccine, Jerusalem, April to July 2022 |
title_sort | emergence of genetically linked vaccine-originated poliovirus type 2 in the absence of oral polio vaccine, jerusalem, april to july 2022 |
topic | Rapid Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479469/ https://www.ncbi.nlm.nih.gov/pubmed/36111556 http://dx.doi.org/10.2807/1560-7917.ES.2022.27.37.2200694 |
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