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Rational design of an anti-cancer peptide inhibiting CD147 / Cyp A interaction
The CD147 / Cyp A interaction is a critical pathway in cancer types and an essential factor in entering the COVID-19 virus into the host cell. Melittin acts as an inhibitory peptide in cancer types by blocking the CD147/ Cyp A interaction. The clinical application of Melittin is limited due to weak...
Autores principales: | Maani, Zahra, Farajnia, Safar, Rahbarnia, Leila, Hosseingholi, Elaheh Zadeh, Khajehnasiri, Nazli, Mansouri, Parisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479519/ https://www.ncbi.nlm.nih.gov/pubmed/36128074 http://dx.doi.org/10.1016/j.molstruc.2022.134160 |
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