(11)C-methionine- and (18)F-FDG-PET double-negative metastatic brain tumor from lung adenocarcinoma with paradoxical high (18)F-FDG uptake: A case report

BACKGROUND: Imaging with 18F-fluorodeoxyglucose (FDG)-positron emission tomography (PET) and (11)C-methionine (MET)-PET can delineate primary and metastatic brain tumors. Lesion size affects the sensitivity of both scans and histopathological features can also influence FDG-PET, but the effects on M...

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Autores principales: Tanahashi, Kuniaki, Hirano, Masaki, Chalise, Lushun, Tsugawa, Takahiko, Okumura, Yuka, Hase, Tetsunari, Ohka, Fumiharu, Motomura, Kazuya, Takeuchi, Kazuhito, Nagata, Yuichi, Nakahara, Norimoto, Hashimoto, Naozumi, Saito, Ryuta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific Scholar 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479527/
https://www.ncbi.nlm.nih.gov/pubmed/36128090
http://dx.doi.org/10.25259/SNI_264_2022
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author Tanahashi, Kuniaki
Hirano, Masaki
Chalise, Lushun
Tsugawa, Takahiko
Okumura, Yuka
Hase, Tetsunari
Ohka, Fumiharu
Motomura, Kazuya
Takeuchi, Kazuhito
Nagata, Yuichi
Nakahara, Norimoto
Hashimoto, Naozumi
Saito, Ryuta
author_facet Tanahashi, Kuniaki
Hirano, Masaki
Chalise, Lushun
Tsugawa, Takahiko
Okumura, Yuka
Hase, Tetsunari
Ohka, Fumiharu
Motomura, Kazuya
Takeuchi, Kazuhito
Nagata, Yuichi
Nakahara, Norimoto
Hashimoto, Naozumi
Saito, Ryuta
author_sort Tanahashi, Kuniaki
collection PubMed
description BACKGROUND: Imaging with 18F-fluorodeoxyglucose (FDG)-positron emission tomography (PET) and (11)C-methionine (MET)-PET can delineate primary and metastatic brain tumors. Lesion size affects the sensitivity of both scans and histopathological features can also influence FDG-PET, but the effects on MET-PET have not been elucidated. CASE DESCRIPTION: We report an unusual case of metastatic brain tumors without accumulation of FDG or MET, contrasting with high FDG uptake in the primary lung lesion. The brain lesions were identified as adenocarcinoma with a more mucus-rich background, contributing to the indistinct accumulation of both FDG and MET. CONCLUSION: Histopathological characteristics can affect both MET and FDG accumulation, leading to findings contradicting those of the primary lesion.
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spelling pubmed-94795272022-09-19 (11)C-methionine- and (18)F-FDG-PET double-negative metastatic brain tumor from lung adenocarcinoma with paradoxical high (18)F-FDG uptake: A case report Tanahashi, Kuniaki Hirano, Masaki Chalise, Lushun Tsugawa, Takahiko Okumura, Yuka Hase, Tetsunari Ohka, Fumiharu Motomura, Kazuya Takeuchi, Kazuhito Nagata, Yuichi Nakahara, Norimoto Hashimoto, Naozumi Saito, Ryuta Surg Neurol Int Case Report BACKGROUND: Imaging with 18F-fluorodeoxyglucose (FDG)-positron emission tomography (PET) and (11)C-methionine (MET)-PET can delineate primary and metastatic brain tumors. Lesion size affects the sensitivity of both scans and histopathological features can also influence FDG-PET, but the effects on MET-PET have not been elucidated. CASE DESCRIPTION: We report an unusual case of metastatic brain tumors without accumulation of FDG or MET, contrasting with high FDG uptake in the primary lung lesion. The brain lesions were identified as adenocarcinoma with a more mucus-rich background, contributing to the indistinct accumulation of both FDG and MET. CONCLUSION: Histopathological characteristics can affect both MET and FDG accumulation, leading to findings contradicting those of the primary lesion. Scientific Scholar 2022-08-19 /pmc/articles/PMC9479527/ /pubmed/36128090 http://dx.doi.org/10.25259/SNI_264_2022 Text en Copyright: © 2022 Surgical Neurology International https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, transform, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Tanahashi, Kuniaki
Hirano, Masaki
Chalise, Lushun
Tsugawa, Takahiko
Okumura, Yuka
Hase, Tetsunari
Ohka, Fumiharu
Motomura, Kazuya
Takeuchi, Kazuhito
Nagata, Yuichi
Nakahara, Norimoto
Hashimoto, Naozumi
Saito, Ryuta
(11)C-methionine- and (18)F-FDG-PET double-negative metastatic brain tumor from lung adenocarcinoma with paradoxical high (18)F-FDG uptake: A case report
title (11)C-methionine- and (18)F-FDG-PET double-negative metastatic brain tumor from lung adenocarcinoma with paradoxical high (18)F-FDG uptake: A case report
title_full (11)C-methionine- and (18)F-FDG-PET double-negative metastatic brain tumor from lung adenocarcinoma with paradoxical high (18)F-FDG uptake: A case report
title_fullStr (11)C-methionine- and (18)F-FDG-PET double-negative metastatic brain tumor from lung adenocarcinoma with paradoxical high (18)F-FDG uptake: A case report
title_full_unstemmed (11)C-methionine- and (18)F-FDG-PET double-negative metastatic brain tumor from lung adenocarcinoma with paradoxical high (18)F-FDG uptake: A case report
title_short (11)C-methionine- and (18)F-FDG-PET double-negative metastatic brain tumor from lung adenocarcinoma with paradoxical high (18)F-FDG uptake: A case report
title_sort (11)c-methionine- and (18)f-fdg-pet double-negative metastatic brain tumor from lung adenocarcinoma with paradoxical high (18)f-fdg uptake: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479527/
https://www.ncbi.nlm.nih.gov/pubmed/36128090
http://dx.doi.org/10.25259/SNI_264_2022
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