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Spexin mRNA profile and its response to different photoperiods in Chinese Yangzhou geese (Anas cygnoides)

Spexin (SPX, NPQ), a novel neuropeptide composed of 14 amino acid residues, is evolutionarily conserved among different species. Spexin has been suggested to have pleiotropic functions in mammals. However, reports on spexin in birds are limited. To clarify the role of spexin in goose reproduction, t...

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Autores principales: Liu, Jie, Dai, Shudi, Shao, Xibing, Wei, Chuankun, Dai, Zichun, Yang, Pengxia, Lei, Mingming, Chen, Rong, Zhu, Huanxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479540/
https://www.ncbi.nlm.nih.gov/pubmed/36118333
http://dx.doi.org/10.3389/fvets.2022.961431
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author Liu, Jie
Dai, Shudi
Shao, Xibing
Wei, Chuankun
Dai, Zichun
Yang, Pengxia
Lei, Mingming
Chen, Rong
Zhu, Huanxi
author_facet Liu, Jie
Dai, Shudi
Shao, Xibing
Wei, Chuankun
Dai, Zichun
Yang, Pengxia
Lei, Mingming
Chen, Rong
Zhu, Huanxi
author_sort Liu, Jie
collection PubMed
description Spexin (SPX, NPQ), a novel neuropeptide composed of 14 amino acid residues, is evolutionarily conserved among different species. Spexin has been suggested to have pleiotropic functions in mammals. However, reports on spexin in birds are limited. To clarify the role of spexin in goose reproduction, the spexin gene was cloned and analyzed. Analysis of tissue distribution by RT-PCR showed that the expression of spexin and its two receptors was widespread. During the long photoperiod, the expression levels of spexin in the pituitary and hypothalamus and of GALR2/3 in the pituitary decreased, and the GnRH, LHβ, and FSHβ expression levels increased significantly. This suggests that a long photoperiod regulates reproductive activities by activating the gonadotrope-axis, which is modulated by decreased spexin levels.
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spelling pubmed-94795402022-09-17 Spexin mRNA profile and its response to different photoperiods in Chinese Yangzhou geese (Anas cygnoides) Liu, Jie Dai, Shudi Shao, Xibing Wei, Chuankun Dai, Zichun Yang, Pengxia Lei, Mingming Chen, Rong Zhu, Huanxi Front Vet Sci Veterinary Science Spexin (SPX, NPQ), a novel neuropeptide composed of 14 amino acid residues, is evolutionarily conserved among different species. Spexin has been suggested to have pleiotropic functions in mammals. However, reports on spexin in birds are limited. To clarify the role of spexin in goose reproduction, the spexin gene was cloned and analyzed. Analysis of tissue distribution by RT-PCR showed that the expression of spexin and its two receptors was widespread. During the long photoperiod, the expression levels of spexin in the pituitary and hypothalamus and of GALR2/3 in the pituitary decreased, and the GnRH, LHβ, and FSHβ expression levels increased significantly. This suggests that a long photoperiod regulates reproductive activities by activating the gonadotrope-axis, which is modulated by decreased spexin levels. Frontiers Media S.A. 2022-09-02 /pmc/articles/PMC9479540/ /pubmed/36118333 http://dx.doi.org/10.3389/fvets.2022.961431 Text en Copyright © 2022 Liu, Dai, Shao, Wei, Dai, Yang, Lei, Chen and Zhu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Veterinary Science
Liu, Jie
Dai, Shudi
Shao, Xibing
Wei, Chuankun
Dai, Zichun
Yang, Pengxia
Lei, Mingming
Chen, Rong
Zhu, Huanxi
Spexin mRNA profile and its response to different photoperiods in Chinese Yangzhou geese (Anas cygnoides)
title Spexin mRNA profile and its response to different photoperiods in Chinese Yangzhou geese (Anas cygnoides)
title_full Spexin mRNA profile and its response to different photoperiods in Chinese Yangzhou geese (Anas cygnoides)
title_fullStr Spexin mRNA profile and its response to different photoperiods in Chinese Yangzhou geese (Anas cygnoides)
title_full_unstemmed Spexin mRNA profile and its response to different photoperiods in Chinese Yangzhou geese (Anas cygnoides)
title_short Spexin mRNA profile and its response to different photoperiods in Chinese Yangzhou geese (Anas cygnoides)
title_sort spexin mrna profile and its response to different photoperiods in chinese yangzhou geese (anas cygnoides)
topic Veterinary Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479540/
https://www.ncbi.nlm.nih.gov/pubmed/36118333
http://dx.doi.org/10.3389/fvets.2022.961431
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