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Kimura’s disease: A short study of cytomorphologic features with its differential diagnosis and review of literature

Kimura’s disease (KD) is a chronic inflammatory disorder of unknown etiology, endemic in Asia. The typical clinical manifestations include a triad of painless unilateral cervical lymphadenopathy or subcutaneous masses predominantly in the head-and-neck region, blood and tissue eosinophilia, and elev...

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Autores principales: Sahu, Priya, Jain, Swasti, Kaushal, Manju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific Scholar 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479607/
https://www.ncbi.nlm.nih.gov/pubmed/36128469
http://dx.doi.org/10.25259/Cytojournal_77_2020
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author Sahu, Priya
Jain, Swasti
Kaushal, Manju
author_facet Sahu, Priya
Jain, Swasti
Kaushal, Manju
author_sort Sahu, Priya
collection PubMed
description Kimura’s disease (KD) is a chronic inflammatory disorder of unknown etiology, endemic in Asia. The typical clinical manifestations include a triad of painless unilateral cervical lymphadenopathy or subcutaneous masses predominantly in the head-and-neck region, blood and tissue eosinophilia, and elevated serum immunoglobulin (Ig) E levels. Many conditions including benign and malignant may mimic KD clinically. This study reports cytologic features of seven cases of KD which were studied and correlated with histology, Ig profile, and peripheral blood examination. KD shows a good response to medical treatment; hence, fine-needle aspiration cytology in conjunction with other laboratory findings lowers the need for additional biopsy procedures for early diagnosis as well as diagnosis of recurrent lesions.
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spelling pubmed-94796072022-09-19 Kimura’s disease: A short study of cytomorphologic features with its differential diagnosis and review of literature Sahu, Priya Jain, Swasti Kaushal, Manju Cytojournal Case Series Kimura’s disease (KD) is a chronic inflammatory disorder of unknown etiology, endemic in Asia. The typical clinical manifestations include a triad of painless unilateral cervical lymphadenopathy or subcutaneous masses predominantly in the head-and-neck region, blood and tissue eosinophilia, and elevated serum immunoglobulin (Ig) E levels. Many conditions including benign and malignant may mimic KD clinically. This study reports cytologic features of seven cases of KD which were studied and correlated with histology, Ig profile, and peripheral blood examination. KD shows a good response to medical treatment; hence, fine-needle aspiration cytology in conjunction with other laboratory findings lowers the need for additional biopsy procedures for early diagnosis as well as diagnosis of recurrent lesions. Scientific Scholar 2022-09-05 /pmc/articles/PMC9479607/ /pubmed/36128469 http://dx.doi.org/10.25259/Cytojournal_77_2020 Text en © 2022 Cytopathology Foundation Inc, Published by Scientific Scholar https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Series
Sahu, Priya
Jain, Swasti
Kaushal, Manju
Kimura’s disease: A short study of cytomorphologic features with its differential diagnosis and review of literature
title Kimura’s disease: A short study of cytomorphologic features with its differential diagnosis and review of literature
title_full Kimura’s disease: A short study of cytomorphologic features with its differential diagnosis and review of literature
title_fullStr Kimura’s disease: A short study of cytomorphologic features with its differential diagnosis and review of literature
title_full_unstemmed Kimura’s disease: A short study of cytomorphologic features with its differential diagnosis and review of literature
title_short Kimura’s disease: A short study of cytomorphologic features with its differential diagnosis and review of literature
title_sort kimura’s disease: a short study of cytomorphologic features with its differential diagnosis and review of literature
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479607/
https://www.ncbi.nlm.nih.gov/pubmed/36128469
http://dx.doi.org/10.25259/Cytojournal_77_2020
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