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Point prevalence of hip symptoms, radiographic, and symptomatic OA at five time points: The Johnston County Osteoarthritis Project, 1991–2018

OBJECTIVE: To describe the point prevalence of hip symptoms, radiographic hip osteoarthritis (rHOA), severe rHOA, and symptomatic rHOA (sxHOA) at five time points in the longitudinal, population-based Johnston County Osteoarthritis Project (JoCoOA). DESIGN: Data were from 3068 JoCoOA participants wh...

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Autores principales: Nelson, Amanda E., Hu, David, Arbeeva, Liubov, Alvarez, Carolina, Cleveland, Rebecca J., Schwartz, Todd A., Murphy, Louise B., Helmick, Charles G., Callahan, Leigh F., Renner, Jordan B., Jordan, Joanne M., Golightly, Yvonne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479672/
https://www.ncbi.nlm.nih.gov/pubmed/36118130
http://dx.doi.org/10.1016/j.ocarto.2022.100251
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author Nelson, Amanda E.
Hu, David
Arbeeva, Liubov
Alvarez, Carolina
Cleveland, Rebecca J.
Schwartz, Todd A.
Murphy, Louise B.
Helmick, Charles G.
Callahan, Leigh F.
Renner, Jordan B.
Jordan, Joanne M.
Golightly, Yvonne M.
author_facet Nelson, Amanda E.
Hu, David
Arbeeva, Liubov
Alvarez, Carolina
Cleveland, Rebecca J.
Schwartz, Todd A.
Murphy, Louise B.
Helmick, Charles G.
Callahan, Leigh F.
Renner, Jordan B.
Jordan, Joanne M.
Golightly, Yvonne M.
author_sort Nelson, Amanda E.
collection PubMed
description OBJECTIVE: To describe the point prevalence of hip symptoms, radiographic hip osteoarthritis (rHOA), severe rHOA, and symptomatic rHOA (sxHOA) at five time points in the longitudinal, population-based Johnston County Osteoarthritis Project (JoCoOA). DESIGN: Data were from 3068 JoCoOA participants who attended up to five study visits (1991–2018). Standardized supine pelvis radiographs were read by a single, expert musculoskeletal radiologist with high reliability. The four outcomes were: 1) self-reported hip symptoms: “On most days, do you have pain, aching, or stiffness in your right/left hip?“; 2) rHOA: Kellgren-Lawrence grade (KLG) of 2–4; 3) severe rHOA: KLG of 3–4; and 4) sxHOA: both symptoms and rHOA in the same joint. Weighted point prevalence and 95% confidence intervals (CI) were generated overall and by age group (45–54, 55–64, 65–74, 75+ years), sex, race (Black/White), and body mass index (BMI; 18.5–24.9; 25–29.9; 30+ kg/m(2)). RESULTS: At the most recent follow-up (2017–2018), the point prevalence (%) of hip symptoms, rHOA, severe rHOA, and sxHOA were 30% (95% CI 25%, 35%), 53% (95% CI 48%, 58%), 9% (95% CI 6%, 12%), and 15% (95% CI 11%, 19%), respectively. RHOA and severe rHOA were most prevalent in those 75+ years. Women were more likely than men to have hip symptoms and sxHOA. No consistent trends were noted by race or BMI. CONCLUSION: These updated point prevalence estimates demonstrate a large and increasing burden of HOA in the general population, particularly with aging. Black and White individuals were affected similarly in this cohort.
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spelling pubmed-94796722022-09-16 Point prevalence of hip symptoms, radiographic, and symptomatic OA at five time points: The Johnston County Osteoarthritis Project, 1991–2018 Nelson, Amanda E. Hu, David Arbeeva, Liubov Alvarez, Carolina Cleveland, Rebecca J. Schwartz, Todd A. Murphy, Louise B. Helmick, Charles G. Callahan, Leigh F. Renner, Jordan B. Jordan, Joanne M. Golightly, Yvonne M. Osteoarthr Cartil Open ORIGINAL PAPER OBJECTIVE: To describe the point prevalence of hip symptoms, radiographic hip osteoarthritis (rHOA), severe rHOA, and symptomatic rHOA (sxHOA) at five time points in the longitudinal, population-based Johnston County Osteoarthritis Project (JoCoOA). DESIGN: Data were from 3068 JoCoOA participants who attended up to five study visits (1991–2018). Standardized supine pelvis radiographs were read by a single, expert musculoskeletal radiologist with high reliability. The four outcomes were: 1) self-reported hip symptoms: “On most days, do you have pain, aching, or stiffness in your right/left hip?“; 2) rHOA: Kellgren-Lawrence grade (KLG) of 2–4; 3) severe rHOA: KLG of 3–4; and 4) sxHOA: both symptoms and rHOA in the same joint. Weighted point prevalence and 95% confidence intervals (CI) were generated overall and by age group (45–54, 55–64, 65–74, 75+ years), sex, race (Black/White), and body mass index (BMI; 18.5–24.9; 25–29.9; 30+ kg/m(2)). RESULTS: At the most recent follow-up (2017–2018), the point prevalence (%) of hip symptoms, rHOA, severe rHOA, and sxHOA were 30% (95% CI 25%, 35%), 53% (95% CI 48%, 58%), 9% (95% CI 6%, 12%), and 15% (95% CI 11%, 19%), respectively. RHOA and severe rHOA were most prevalent in those 75+ years. Women were more likely than men to have hip symptoms and sxHOA. No consistent trends were noted by race or BMI. CONCLUSION: These updated point prevalence estimates demonstrate a large and increasing burden of HOA in the general population, particularly with aging. Black and White individuals were affected similarly in this cohort. Elsevier 2022-03-15 /pmc/articles/PMC9479672/ /pubmed/36118130 http://dx.doi.org/10.1016/j.ocarto.2022.100251 Text en © 2022 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle ORIGINAL PAPER
Nelson, Amanda E.
Hu, David
Arbeeva, Liubov
Alvarez, Carolina
Cleveland, Rebecca J.
Schwartz, Todd A.
Murphy, Louise B.
Helmick, Charles G.
Callahan, Leigh F.
Renner, Jordan B.
Jordan, Joanne M.
Golightly, Yvonne M.
Point prevalence of hip symptoms, radiographic, and symptomatic OA at five time points: The Johnston County Osteoarthritis Project, 1991–2018
title Point prevalence of hip symptoms, radiographic, and symptomatic OA at five time points: The Johnston County Osteoarthritis Project, 1991–2018
title_full Point prevalence of hip symptoms, radiographic, and symptomatic OA at five time points: The Johnston County Osteoarthritis Project, 1991–2018
title_fullStr Point prevalence of hip symptoms, radiographic, and symptomatic OA at five time points: The Johnston County Osteoarthritis Project, 1991–2018
title_full_unstemmed Point prevalence of hip symptoms, radiographic, and symptomatic OA at five time points: The Johnston County Osteoarthritis Project, 1991–2018
title_short Point prevalence of hip symptoms, radiographic, and symptomatic OA at five time points: The Johnston County Osteoarthritis Project, 1991–2018
title_sort point prevalence of hip symptoms, radiographic, and symptomatic oa at five time points: the johnston county osteoarthritis project, 1991–2018
topic ORIGINAL PAPER
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9479672/
https://www.ncbi.nlm.nih.gov/pubmed/36118130
http://dx.doi.org/10.1016/j.ocarto.2022.100251
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